Abstract

The Coronavirus disease 2019 (COVID-19) Reporting and Data System (CO-RADS) is a standardized Computed Tomography (CT) assessment tool for COVID-19 pneumonia. However, its correlation with hematological parameters needs further investigation. This study aimed to evaluate the relationship between CO-RADS scores and hemogram parameters in COVID-19 patients and assess their potential role in predicting disease severity. This retrospective study included 6,703 Polymerase Chain Reaction (PCR)-confirmed COVID-19 patients who presented to the emergency department between March 15 and June 15, 2020. Patients were classified according to CO-RADS scoring [1-5], and their demographic data, hemogram parameters, and CT findings were analyzed. The relationship between CO-RADS scores and laboratory parameters was evaluated, and ROC analysis was performed to determine cut-off values for predicting severe disease (CO-RADS 4-5). The mean age of patients was 56.8±17.2 years, and 48% were female. Analysis revealed significant correlations between CO-RADS scores and various hemogram parameters. Higher CO-RADS scores correlated with elevated white blood cell (WBC), neutrophils, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-to-lymphocyte ratio (MLR), while lymphocytes decreased (p

Key words: COVID-19, CO-RADS, computed tomography, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, disease severity