Seroprevalence of Hepatitis A Virus in Inonu University Medical Faculty Hospital, 2015
Yucel Duman, Mehmet Sait Tekerekoglu, Selma Ay, Ayfer Serindag.
Abstract
Hepatitis A is the most common pathogen that causes acute viral hepatitis in humans. HAV infection is considered as an important public health concern. The aim of this study was to assess the seroprevalence of anti-HAV IgG and IgM antibodies in our hospital. The presence of anti-HAV IgG and IgM antibodies were evaluated retrospectively from 7275 serum samples which sent to our hospitals microbiology laboratory in 2015. The presence of anti-HAV IgG and IgM antibodies in serum samples were studied by using macro ELISA Abbott - Architect i2000 system test kits. The 7275 patients serum samples were analyzed. The 74.4% of analyzed samples were positive for anti-HAV IgG antibodies. Anti-HAV IgM antibody positivity rate was found as 1.3%. The 87.4% of anti-HAV IgM positive cases were under the age of 16 and 12.6% were at adulthood stage. The incidence of acute viral hepatitis disease could be reduced by improving hygiene conditions, personal hygiene education, routine vaccination activities, correcting infrastructure and informing people about HAV. We believe that; the data contributes to evaluate the preventive measures, immunization program studies and determination of vaccine efficacy studies.
Key words: Hepatitis A, seroprevalence, anti-HAV IgG
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