Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide, yet many populations remain underserved in terms of timely screening. Various evidence-based interventions (EBIs) were developed to improve colorectal cancer screening (CRCS) rates, but their implementation faces several challenges. Understanding the facilitators and barriers to the implementation of these interventions is crucial to improving their effectiveness. This review synthesized the findings of studies that examined the implementation of EBIs for CRC screening, focusing on both facilitators and barriers identified across various health care settings. Data from qualitative and quantitative studies were analyzed to determine common themes related to intervention characteristics, the internal and external settings, and the characteristics of individuals involved in the implementation process. The analysis revealed several key facilitators of CRCS intervention implementation. These included strong leadership engagement, clear communication within clinic teams, the adaptability of interventions, and continuous monitoring and feedback. Conversely, barriers to successful implementation were commonly related to resource limitations, lack of coordination between staff, challenges in patient engagement, and issues with electronic medical record. Additionally, patient-related barriers such as low health literacy, fear, and logistical issues were significant obstacles to screening participation. Successful implementation of CRC screening interventions requires a multi-dimensional approach that includes leadership support, clear communication, adequate resources, and strategies to engage patients. Addressing the identified barriers, particularly in terms of communication, resource allocation, and patient education, is essential for improving CRCS outcomes.
Key words: Early detection, strategies, colorectal cancer, family medicine, systematic review
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