Mistletoes are evergreen and semi parasitic plant growing on a variety of tree and shrubs. They have been used in the treatment and management of many diseases for many years, both traditional and complementary medicine such as diarrhea, cough, diabetes, hypertension and cancer. The purpose of this study was to determine the antimicrobial activity of Korean camellia mistletoe (Korthalsella japonica (Thunb.) Engl.) depending on the harvest time (August and November 2015) and solvent (100% methanol and 70% ethanol). Antimicrobial activity of methanol and ethanol extracts was subject to screening against two gram positive (S. epidermidis and B. subtilis subsps.) and negative bacillus (K. pneumonia and E. coli) by using disc diffusion method and measured by the size of clear zone (diameter, mm). The results showed that methanol extract was slight effective in 15 mg/mL concentration on all strains regardless of harvest time, while ethanol extract has no certain antimicrobial effect on both gram positive and negative bacillus. The results obtained in this study suggested that the extracts have low potential for use in the treatment of diseases caused by these test organisms and futher studies are necessary to evaluate the anti-bacterial efficiency of Korean camellia mistletoe against different bacterial strains.
Key words: Antimicrobial activity, Korean camellia mistletoe, disc diffusion, solvent extraction
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