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Review Article

IJMDC. 2025; 9(9): 2110-2117


A systematic review and meta-analysis comparing the effects of labetalol and hydralazine for hypertension on fetal and neonatal outcomes in pre-eclampsia

Rakan Abdullah Alsulami, Rawan Gari, Nujud Binhudayb, Eyad Algolagah, Amna Majed, Shahad Al Fadel, Faye Faisal Afandy, Waad Obaidallah Aljadani, Asseel Ali Alaidarous, Albatool Mohammed Alshaqha.



Abstract
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There is a lack of comparative data on the effects of hydralazine and labetalol on fetal and neonatal outcomes in pre-eclamptic patients. This systematic review and meta-analysis aimed to compare their impacts on fetal heart rate (FHR) abnormalities, 1-minute appearance, pulse, grimace, activity, and respiration (APGAR) scores

Key words: Pre-eclampsia, hydralazine, labetalol, fetal and neonatal outcomes, systemic review

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