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Review Article

IJMDC. 2025; 9(1): 185-194


Predictors of Airway Compromise in Patients with Angioedema Presenting to the Emergency Room

Mahmoud Fekry Hassan Hassebo, Ahmed Fareed Samman, Faisal Hassan Sindi, Juri Jalal Alamri, Kubra Taha Al Ossaif, Garam Alhunaki, Shoroq Abdullatif Aljohni, Saud Fahad Saud Al Shuaibi, Farah Saleh Allabun, Suhib Rebhi Elaiwah, Hissah Khazzam M. Aldawsari.




Abstract

Angioedema is characterized by the rapid swelling of the deeper layers of the skin, often affecting the face, lips, tongue, and throat. In emergency settings, airway compromise is a significant concern due to the potential for airway obstruction. Several predictors can aid in identifying patients at higher risk for airway emergencies. These include the duration of the swelling, the involvement of the tongue or oropharynx, associated respiratory symptoms, and a known history of previous angioedema episodes. Rapid progression and the presence of associated symptoms such as dysphagia or stridor may also indicate an increased risk of airway obstruction, warranting immediate intervention. Other key risk factors include the patient’s age, underlying health conditions (such as asthma or chronic obstructive pulmonary disease), and any potential triggers, such as medication use or allergic reactions. Past medical history can provide crucial insights; patients with hereditary angioedema or those who have previously experienced severe airway compromise are at greater risk. Clinicians should conduct a thorough assessment, including visual inspection and auscultation of the airway, to anticipate and manage potential complications effectively. Early recognition and timely intervention can significantly improve patient outcomes in these high-risk situations.

Key words: Angioedema, airway compromise, emergency room, predictors, swelling, respiratory symptoms, dysphagia.






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