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Original Article

IJMDC. 2025; 9(1): 070-076


Cross-sectional study on the relationship between ABO and Rh blood groups with alopecia in the western region, Saudi Arabia

Shaden O. Alqurashi, Ghadah M. Almutairi, Safiah O. Aldabali, Retaj W. Calacattawi, Areej N. Alzahrani, Wesam S. Alharbi, Maha B. Elbadawy, Ahmed M. Bin Mahfoz, Sama H. Alfaki, Ghaliah O. Alnefaie.




Abstract

Objective: This study aimed to determine if there is a correlation between ABO, Rh blood group, and alopecia areata (AA).
Methods: A cross-sectional study was conducted on a sample of 118 cases with AA and 200 healthy controls (HCs) from the dermatological departments of hospitals in the western region, of Saudi Arabia. Data were collected using a self-administered questionnaire.
Results: The study showed that females represented the majority of participants and that a significant percentage was of the 25 to 28 years-old age range, recruited majorly from the Western region. When it came to blood types, O+ was the most prevalent at 48%. It also had the largest frequency of alopecia, with 65 cases (29.15%), and alopecia was more common and seemed to be more severe in O+ blood group participants. The majority of participants (23.1%) who had alopecia had the condition for more than a year.
Conclusion: The findings revealed no significant correlation between the blood type and the incidence, severity, pattern, duration of alopecia, or changes in nails, despite the reported patterns.

Key words: Alopecia areata, ABO blood groups, hair loss patterns, autoimmune disorders, Saudi Arabia.






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