Abstract

Epidermolysis bullosa (EB) is a rare genetic disorder characterized by skin and mucosal fragility that leads to exaggerated blister formation triggered by minor trauma or occurring spontaneously. Squamous cell carcinoma develops at a younger age compared to other populations, especially in recessive dystrophic EB (DEB) subtypes. Ensuring skin and mucosal integrity is crucial in anesthesia monitoring and airway management for EB patients. Here, we present the case of a 23-year-old woman diagnosed with DEB, presenting with intraoral blisters and scheduled for excision of squamous cell carcinoma of the foot. Spinal anesthesia was administered for the patient’s anesthetic management. It should be remembered that spinal anesthesia can be a suitable method in patients with dry and infection-free skin at the puncture site.

Key words: Epidermolysis bullosa, spinal anesthesia, squamous cell carcinoma