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Correlation of serum Vitamin D, calcium, and albumin levels with bone mineral density in young adults: A cross-sectional study

Vimal Kumar Chaurasiya, Jalaj Saxena, Suman Lata Verma, Dolly Rastogi, Saurabh Saha, Atosh Kumar, Anupama Gupta, Jay Vardhan Singh, Preeti Kanawjia.




Abstract

Background:
The World Health Organization has recognized India as one of the nations with the highest prevalence of lifestyle sickness. It is quickly becoming the capital of lifestyle-related diseases due to starvation and a shortage of food, which are the main issues in developing countries like India. Studies suggest that a significant proportion of Indians, ranging from 4% to 26%, living in both rural and urban areas, irrespective of their age, may not have access to sufficient amounts of protein, calcium, and other essential vitamins.

Aim:
This cross-sectional study investigates the correlation between serum vitamin D, calcium, and albumin levelswith bone mineral density (BMD) among young adults aged 18–25 years at GSVM Medical College, Kanpur, India.

Methods:
A sample of 150 participants was analyzed using anthropometric measurements, dietary habits, physical activity, and biochemical assessments, including serum vitamin D, calcium, and albumin levels. BMD was measured using Dual-Energy X-ray Absorptiometry.

Results:
Revealed no statistically significant relationships between BMD and the serum levels of vitamin D, calcium, or albumin. Specifically, Pearson’s correlation coefficients for these markers showed weak, non-significant associations with BMD. Regression analysis also demonstrated that age, BMI, and dietary habits did not predict BMD significantly.

Conclusion:
These findings highlight that bone health in young adults is likely influenced by multiple factors beyond conventional biochemical markers, including lifestyle, genetic, and hormonal factors. The study emphasizes the importance of promoting balanced nutrition and regular physical activity to maintain bone health among young individuals.

Key words: Bone mineral density, Vitamin D, Calcium, Albumin, Young adults, Nutrition, Lifestyle






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