ADVERTISEMENT

Home|Journals|Articles by Year|Audio Abstracts
 

Original Article



Hypoglycemic and hypolipidemic effects of Aerva lanata (Linn.) on alloxan induced diabetic rats

Ramalingam Vidhya, Rajangam Udayakumar.



Abstract
Download PDF Cited by 3 ArticlesPost

Diabetes mellitus is a chronic disorder of carbohydrate, protein, fat and mineral metabolism. The antidiabetic potential of aqueous extracts flower and root of Aerva lanata was evaluated in alloxan induced diabetic rats. Alloxan (150 mg/kg bw) induced diabetic rats showed a hyperglycemic state that led to various biochemical and metabolic alterations. The aqueous extract of flower and root of A. lanata (200 mg/kg bw) was administrated orally to diabetic rats for 45 days. In this study, the levels of fasting blood glucose, glycated hemoglobin (HbA1C), C-reactive protein (CRP), total cholesterol, triglycerides (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL), urea, and creatinine were significantly increased in diabetic rats. Body weight, hemoglobin, insulin, C-peptide and protein levels in blood were significantly decreased in alloxan induced diabetic rats. After the administration of extracts of flower and root of A. lanata to diabetic rats showed significantly restore the levels as normal rats. The antidiabetic effect of A. lanata was compared with strandard drug glibenclamide (1 mg/kg bw) treated rats. From this study, we concluded that the aqueous extract of A. lanata root have more antidiabetic effect when compared with flower extract. Therefore, the flower and root of A. lanata may be used as the alternative medicine for the treatment of diabetes mellitus.

Key words: Aerva lanata, alloxan, flower, root, diabetes meilltus, hypoglycemic, hypolipidemic





publications
0
supporting
0
mentioning
0
contrasting
0
Smart Citations
0
0
0
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.



Bibliomed Article Statistics

20
12
20
19
15
35
25
38
41
41
43
52
R
E
A
D
S

26

13

5

12

11

9

15

14

17

14

76

13
D
O
W
N
L
O
A
D
S
080910111201020304050607
20242025

Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Author Tools
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.


We use cookies and other tracking technologies to work properly, to analyze our website traffic, and to understand where our visitors are coming from. More Info Got It!