Abstract

Background:
Most airway obstruction i.e. about 89% occurs during general anesthesia and 70% involve upper airway. Henceforth, choosing an appropriate choice of sedative to decrease the respiratory morbidity during post anesthetic period is utmost important.

Aim:
To analyze the peak expiratory flow rate in propofol & midazolam induced post anesthetic patients separately and compare.

Methods:
This is a comparative study of measuring PEFR in post anesthetic patients between propofol induced and midazolam induced patients. A sample size of 30 were taken, among which 15 were propofol induced and 15 were midazolam induced subjects.

Results:
Mean values of Avg PEFR readings of propofol and midazolam showed a p-value of 0.0001 which is statistically significant. Mean PEFR values of Males and Females in Propofol induction showed a p-value of 0.0007 which is statistically significant. Mean PEFR values of Males and Females in Midazolam induction showed a p-value of 0.0092 which is statistically significant.

Conclusion:
Midazolam significantly depresses respiratory system more than propofol. And females irrespective of the anesthetic drug used for induction showed low PEFR values as compared to males.

Key words: Propofol, Midazolam, PEFR in Anesthesia, Anesthesia in respiratory illness, Comparison between midazolam and propofol in sedation