Aim: The aim of this study was to evaluate the implantation success of local
endometrial injury in patients undergoing intrauterine insemination following ovulation
induction with gonadotropins.
Materials and methods: In this prospective randomized controlled trial, ovulation induction
was performed with gonadotropins in 30 patients following intrauterine insemination. Group
1 was comprised of 30 patients who underwent injury by hysteroscopy; the control group
(Group 2) consisted of 30 patients who underwent hysteroscopy only.
Results: There was no significant difference in the clinical pregnancy (16.6 % [5/30] versus
18.7% [6/32]; p = 0.8), abortion (3.3% [1/30] versus 3.1% [1/32]; p = 0.9) or multiple
pregnancy (3.3% [1/30] versus 3.1% [1/32]; p = 0.9) rates.
Conclusion: No significant difference was found in the clinical pregnancy, multiple
pregnancy or abortion rates between the intervention group, which underwent hysteroscopic
injury in the follicular phase before intrauterine insemination induced by gonadotropins, and
the control group, which underwent hysteroscopy only.
Key words: Office hysteroscopy, intrauterine insemination, endometrial injury, gonadotropin,
infertility
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