Abstract

This research aimed to ascertain if raw camel milk ingestion via oral route; may be hepatotoxic; marked by hyper release of some hepatic enzymes or otherwise. The study measured levels of some liver enzymes; that usually become altered due to liver cells injury. Sustained hypertension consequent L-NAME chronic use; may expose recipient hepatic cells to possible injury. Hypertension was induced by L-NAME (50 mgkg-1body weight/day) oral administration to 5 groups (each with 5 rats) and it was verified by periodic blood pressure measurement over 4 weeks. Three control groups used were positive that received amlodipine drug (10 mgkg-1 b.w/day) and negative; devoid of any received intervention (only L-NAME; 50mgkg-1 b.w/day, p.o) and normal control (given only distilled water). Three raw camel milk (CM) treatment groups fragmented as CM1 (100mgkg-1b.w./day), CM3 (300mgkg-1b.w./day) and CM5 (500mgkg-1b.w./day) were administered concurrently with L-NAME (50 mgkg-1b.w.) during treatment time. Results showed statistically significant reduced transaminases (ALT, AST) and alkaline phosphatase values; for p-value (1-way test chi square approximation or if p is

Key words: Hypertensive, liver cells damage, L-NAME, raw camel milk