Aim: To evaluate renal biochemical and some electrolyte changes induced by lead acetate (PbA) and the ameliorative effect of aqueous extract of Adansonia digitata fruit pulp (AEADFP) in Clarias gariepinus.
Methods: A total of 120 Clarias gariepinus weighing between 185 ± 5 g were assigned randomly into 6 treatment groups (A, B, D, E and F) of n=20. Group A was administered borehole water for 35 days; Group B, C, D, E and F were administered PbA for 14 days and subsequently borehole water, 195 mg/L of AEADFP, 390 mg/L of AEADFP, 585 mg/L of AEADFP and 15 mg/L of dimercaptosuccinic acid (DMSA), respectively, for 21 days. Four fish per group were randomly selected on weekly basis for blood sampling, and serum biochemical analysis of renal function markers and some electrolytes.
Results: There was considerable (P
Key words: Adansonia digitata, Clarias gariepinus, Electrolytes, Lead acetate, Nephrotoxicity
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