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Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus

Huseyin Kurt, Davut Demirkiran.




Abstract
Cited by 8 Articles

Background: Mean platelet volume (MPV) level is known to increase in diabetes mellitus (DM).
Objective: In this study, the first aim is to examine whether there is a correlation between MPV and hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG). The second aim is to investigate whether a correlation exists between MPV and HbA1c and FPG changes after treatment
Method: In the study, we examined baseline and final HbA1c, MPV and FPGA values of 343 patients. Including the study group (SG) consisted of 169 patients with diabetes whose HbA1c levels decreased %1 and the control group involving 174 patients whose HbA1c levels did not change.
Results: Similar to CG, HbA1c level of SG decreased to 7.58, and MPV level reduced to 8.68. There existed a positive correlation between MPV and HbA1c levels (r=154; p

Key words: Mean platelet volume, diabetes mellitus, hemoglobin A1c, fasting plasma glucose. 






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