Objective: To examines the Reference Interval (RI) of LDL-C and HDL-C in Jazan, Southwest Saudi Arabia.
Methodology: A minimum of 120 participants from a healthy population were selected and serum levels HDL and LDL were quantified. The RI was established by identifying the upper and lower boundaries based on the outermost 5% of observations. A total of 2.5% of individuals with the lowest scores and 2.5% of persons with the highest scores were omitted from reference range.
Results: RI of LDL in males ranged from 2.25 to 3.47 mmol/L, whereas in females it ranged from 2.35 to 3.77 mmol/L. The lower limit of LDL RI was determined to be 2.25 mmol/L for men and 2.35 mmol/L for women, which is slightly below the reported normal value of 2.5 mmol/L. The maximum limit for females (3.77 mmol/L) exceeded the normal value of 3.4 mmol/L.
Conclusion: The HDL/LDL values were 2.39, 2.07, and 2.27 for the male, female, and whole samples. The obtained RIs in this investigation exhibit a level of comparability with the standard worldwide RI.
Key words: Blood lipids, cholesterol, reference intervals, Southwest Saudi Arabia.
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