Objective: Brain natriuretic peptides are the marker protein structures released in response to wall tension from ventricular myocytes, and have been increasingly used in recent years. The use of N-Terminal Prohormone Brain Natriuretic Peptide is getting more expanded in acute heart failure, left ventricular diseases and acute dyspnea. Here, we aimed at investigating the level of N-Terminal Prohormone Brain Natriuretic Peptide in patients diagnosed with arrhythmias.
Methods: Patients admitted to the emergency department and with any rhythm disorder were included into this study. Bedside echocardiography was performed for each patient. Patients were classified into two groups with and without heart failure. Blood samples of 1 cc were drawn from patients and put into ethylene diamine tetraacetic acid (EDTA)-containing tubes, and N-Terminal Prohormone Brain Natriuretic was investigated. Collected data were recorded into the prepared forms. Statistical analyses were performed with SPSS for Windows 13.0 software package. While average N-Terminal Prohormone Brain Natriuretic level was 25100±10955 pg/Ml in patients with heart failure, average level of N-Terminal Prohormone Brain Natriuretic was seen as 5767.61±6225 pg/mL in those with any rhythm disorder but no heart failure.
Conclusion: N Terminal Prohormon Brain Natriuretik Peptid are important markers in the diagnosis of acute heart failure. In recent years, studies on their association with other diseases have become widespread. In our study, we also found BNP levels more than normal ranges in patients with arrhythmia but no cardiac failure, as well as finding N-Terminal Prohormone Brain Natriuretic levels at higher rates in heart failure patients with dysrhythmia.
Key words: Arhythmia; N-Terminal Prohormone Brain Natriuretic; Heart Failure.
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