In this study we aimed to determine the susceptibility of Salmonella (n: 30) and Shigella (n: 26) strains commonly iso/ated from patients having infectious diarrheae in Turgut Özal Medical Çenter to ampicillin, co- trimoxazoie, chloramphenicol and quinoiones which are antibiotics used in empirical treatment of acute infectious diarrheae. Disk diffusion method was used to test susceptibility patterns.
AH Salmonella and Shigella strains were susceptible to quinolones. The resistance percentages of Salmonella strains were 66 %, 42.3 % and 33.3 %, to ampicillin, chloramphenicol and co-trimoxazoie, respectively while the resistance rates of Shigella spp to the same corresponding antimicrobials were 50 %, 53.8 % and 19.2 %, respectively. From these resu/ts, it can be conduded that quinolones are the drugs of choice in empirical therapy of Salmonella and Shigella gastroenteritis. In therapy of infectious diarrhea of known etioiogy, results of antimicrobial susceptibility must be taken into consideration for addressing the effective antimicrobial agent.
Key words: Salmonella, Shigella, diarrhea, antibiotic resistance
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