Surface membran antigen analysis (immunophenotyping) and DNA content analysis are the two most common applications offlow cytometry in oncology field. Surface membrane antigen analysis is used in the diagnosis and classification of leukemias and lymphomas. Flow cytometric immunophenotyping is helpful for monitoring of patients and also has prognostic value. The technology of flow cytometry and monoclonal antibody have added new dimensions in the evaluation of leukemias and lymphomas. In this study immunophenotypic features of hematologic malignancies are reviewed. [Journal of Turgut Ozal Medical Center 1996;3(2):130-136]
Key Words: Flow cytometry, immunophenotyping, leukemia, lymphoma
|