Comparison of Immunological Effect of Propofol and Thiopentone on the Immune System
Mustafa Altındiş1, MD, PhD, Emel Türk Arıbaş2, MD, Ali Kart3, MD, Celalettin Vatansev4, MD,A. Zeki Şengil5, PhD
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Abstract
This study was designed to compare the immunological effect of thiopentone with propofol. By using TIVA technique first group patients were infused with propofol and second group infused with thiopentone. Many immunological and haematological tests were studied on samples obtained 30 min. before, 30 min. and 24 hr after the operation. The PPD test was also implemented before and after two days of anaesthesia. In the study at postoperative 30h min. decrease of IgG, IgM, IgA and C3 in the group used propofol and decrease of IgM, IgA and C4 in the group used thiopentone were significant (p
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