Abstract

 


Clomiphene citrate is commonly used for ovulation induction. While the ovulation rate is 85% in stimulated cycles, the pregnancy rate is 40%. The lower pregnancy rates is the result of anti-estrogenic effect of the clomiphene citrate on target organs such as endometrium, and cervix. This study included 48 patients with anovulation. Twenty-four patients received only clomiphene citrate (CC), the remaining 24 patients received CC plus conjugated estrogen. The levels of serum testosteron (T) were low on 14th day, but the levels of serum estradiol (E2) were high in the studied group (p0.05). When the levels of serum T on 14th day were compared with the other parameters, there was a significant difference between both groups (p