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Original Research

Ann Med Res. 2004; 11(4): 227-231


Detection of Herpes simplex Virus type-1 and 2 (HSV-1 and HSV-2) IgG and IgM Antibodies with ELISA in Sera of Pregnant Women

S.Aslıhan Cengiz*, Lügen Cengiz**, Ebru Us***, A.Tevfik Cengiz***

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Abstract


ELISA in the sera of pregnant women.

Material and Method: 8-10 ml venous blood were taken from 96 pregnant women in different periods of their

pregnancies and centrifuged in Department of Microbiology, Ankara University Faculty of Medicine, Laboratory of

serology. The tests were performed in accordance with test guides and the results were read in EL-9 Microplate

reader.

Results: HSV-1 IgG was positive in 71/96 (%74) women. HSV-1 IgM was positive in only one women. HSV-2 IgG

was positive in %62.5 (60/96) and IgM in %11.5 (11/96) women. The HSV-2 IgM seropositivity was seen between

15-30 years of age.

Conclusions: In a community the HSV infection before and after the pregnancy is an important health problem

especially for infants. Therefore, it is useful to investigate the HSV-1 and 2 antibodies in the pregnanat womens’

sera.

Key Words: Pregnants, Herpes simplex virus, ELISA, Antibody






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