Abstract

 

Pseudohyperplastic adenocarcinoma is a recently described rare type of prostatic adenocarcinoma with deceptively benign architectural features. Pseudohyperplastic pattern mimics benign glands owing to their papillary infoldings,luminal indulations, large size and occasional corpora amylacea. The main morphologic features helpful in establishing the malignancy are; nuclear enlargement, occasional to frequent nucleoli and total absence of basal cells.  The diagnostic significance of this pattern lies in its potential to be misdiagnosed as benign prostate glands and adenosis. Herein we report a case of a pseudohyperplastic carcinoma and a brief review of the literature.

Key Words: Pseudohyperplastic prostatic adenocarcinoma, Gleason grade, Prostate cancer