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Review Article

Ann Med Res. 2010; 17(4): 413-422


The Investigation of Effect Mechanism, Chemical Structure and Toxicokinetics Properties of Dioxins Compounds

 

Osman Çiftçi*

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Abstract


 

Dioxin compounds are environmental pollutants that have a wide range of diffusion and that are harmful for human and animal health. The dioxin compounds are formed by some chemical process and high temperature. They are taken by human beings through animal products and then stored in fat tissues. The dioxin compounds have many side effects including immune system disrupts, chloracne, wasting syndrome, endocrine and reproductive toxicity as well as cancer. As considered the risks of dioxins which may affect the public health, it is important to learn about the sources, chemical structures, effect mechanisms, toxicity, the daily intake rates, and toxicokinetics properties of dioxins.

Key Words: Dioxin; 2,3,7,8-TCDD; PCDD; PCDF; PCB.






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