Single photon emission computed tomography (SPECT) imaging with 99mTc sestamibi is used to assess the location or the extent of myocardial ischemia. Echocardiography has the ability to evaluate wall motion, measurement of left ventricular (LV) volumes and ejection fraction (EF). The goal of this study was to compare measurements of left ventricular geometry parameters in ischemic and non-ischemic patients along with SPECT and echocardiography.
Consecutive 78 patients (mean age 47±14 years, 38 males, 40 females) with suspected coronary artery disease were enrolled. In all patients, SPECT and good-quality echocardiographic recordings were studied retrospectively. Patients were divided into two groups: ischemic (n=27) and non-ischemic (n=51) according to MPS. All patients examined according to the study protocol, which included registration of weight, height, sex and echocardiography data. Echocardiographic parameters were also compared with MPS.
Only end diastolic left ventricular diameter (EDLVD) was significantly higher in the ischemic group than in the nonischemic group (5.1±0.6 vs 4.7±0.8; p0.2); CO (4.6±2.4 vs 4.8±2.4, p>0.05); EF (59.9±11.0 vs 60.2±7.8, p>0.05); FS (23.1±14.2 vs 22.2±16.2, p>0.05); SWT (1.0±0.2 vs 1.0±0.3, p>0.05) and PWT (0.9±0.2 vs 1.0±0.3, p>0.05) parameters in echocardiography between patients with non-ischemic and ischemic, respectively.
Echocardiographically, left ventricular diastolic diameters were significantly higher in patients with ischemic than in non-ischemic patients. Thus, these associated EDLVD differences have given important information about cascade of ischemic heart disease.
Key Words: CAD, Myocard Perfusion Scintigraphy, Echocardiography, End Diastolic Left Ventricular Diameter
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