Chronic prostatitis is an infection that requires long-term antimicrobial therapy. In this study, a chronic prostatitis case is presented, which was caused by an extended spectrum of beta-lactamase-producing E. coli strain, and progressed with recurrent relapses.
A 72 years old patient who admitted to urology clinic with disuria complaint underwent to advanced medical investigation for malignancy by the measurement of the serum PSA levels above 18 ng/ml. Histopathologic examination of his prostate biopsy samples resulted as chronic inflammation with active focuses, after the urine culture yielded E.coli growth with meaningful colony count.
As the isolate was multidrug-resistant, parenteral carbapenem therapy was commenced for the patient. Although serum PSA levels decreased approximately 3-4 fold while he was receiving antimicrobial therapy, it did elevate to high levels again following the therapy’s end. The patient received 4 cures of antibiotherapy in the current year. He is still under consideration to be given antibiotics in acute phases, with urine culture and serum PSA levels measurements.
Key Words: Prostatitis; E.Coli; PSA.
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