Abstract

Introduction: Fanconi’s anemia (FA) is a rare autosomal recessive disorder characterized by aplastic anemia, congenital anomalies, and cancer susceptibility. Vulvar cancer, mostly seen in postmenopausal, is fourth common gynecologic cancer. In this report, we present a 17- years- old virgin patient, who had diagnosis of Fanconi’s anemia 9 years before, with vulvar squamous cell carcinoma.

Case Report: A 17- years-old female presented to our department with complait of growing fragile mass of her vulva which have appeared 2-3 months ago. The vulvar biopsy showed a vulvar squamous cell carcinoma. Despite prompt modified radical vulvectomy-gluteal fold flep closure and radiotherapy lung methastasis was observed two months after the surgery. The prognosis is poor.

Conclusion: Vulvar cancer can be seen with FA in adolescent. These patiens could have poor prognosis despite prompt and agressive treatment. Further studies to evaluate the importance of HPV vaccia ne in patients with FA are needed.

Key Words: Fanconi’s Anemia; Vulvar Cancer.