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Case Report

Dusunen Adam. 2016; 29(3): 286-289


Anti-NMDA receptor encephalitis: a neuropsychiatric entity

Andac Topkan, Sule Bilen, Esra Eruyar, Yesim Sucullu Karadag.




Abstract

AntiNMDA receptor encephalitis is a form of autoimmune encephalitis which manifests itself with acute or subacute onset psychiatric symptoms, seizures, autonomic dysfunction, and movement disorders. It is a rather recently described form which may progress fatal at about 20%, and which may recover with aggressive immunosuppressive treatment without any sequela. Multifocal, non-specific, subcortical white matter lesions can be observed in cranial magnetic resonance imaging. Since mostly it has paraneoplastic etiology, it is crucial to screen for malignancies after the diagnosis. Its diagnosis is very important, because it will lead early diagnosis of a possible mallignancy. In the present article, a case which applied to our outpatient clinic with noisy neuropsychiatric clinical picture, and was diagnosed with anti-NMDA receptor encephalitis after evaluations, and treated with complete recovery, was presented.

Key words: Immunsupressive therapy, neuropsychiatric symptoms, paraneoplastic autoimmune encephalitis






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