Abstract

Peutz–Jeghers syndrome is a rare autosomal dominant genetic disorder characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa. We present a rare case of Peutz-Jeghers syndrome with multiple intussusceptions. A 30 year old female was brought to the emergency room with colicky abdominal pain in umbilical area and lower abdomen, vomiting and blood in stools since 1 day. The lower lip and sole of feet showed hyperpigmented patches. On examination, bowel sounds were increased and rectal examination revealed black tarry stool. Exploratory laprotomy done revealed jejuno-ileal and ileo-cecal intussusceptions for which intestinal resection and anastomosis was done. There were multiple polyps in the resected ileal segment.

Key words: Peutz-Jeghers syndrome, Multiple intussusception