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The Role of External Beam Radiation Therapy in Thyroid Cancer: When and How to Do it

Sadia Sadiq, Rab Nawaz Maken, Areeba Niaz, Abubaker Shahid.



Abstract
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ABSTRACT

External Beam Radiation Therapy (EBRT) involves using high-energy x-rays or particle beams targeted at malignant tissues, with the goal of destroying tumor cells while minimizing damage to healthy surrounding structures. However, the indication and timing of EBRT vary considerably depending on the specific histological subtype of thyroid cancer, the presence of metastatic or unresectable lesions, and individual patient factors such as comorbidities and prior treatments. Moreover, the therapeutic benefit of EBRT must be balanced against potential side effects, making patient selection and protocol design pivotal components in managing advanced thyroid cancer.
This article explores the role of EBRT in thyroid cancer, with particular attention to when it is recommended, the patient populations that benefit most, and how to optimize treatment protocols. By illuminating current best practices and emerging evidence, we aim to guide clinicians in deciding when and how to incorporate EBRT into a multidisciplinary treatment plan for thyroid cancer.

Key words: External beam Radiation Therapy, Ca Thyroid, Indications, Guidelines, Locoregional Control, RT Volumes.







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040506070809101112
2025

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