Trauma patients often present with a variety of comorbidities that can complicate their treatment and impact their overall outcomes. This review aimed to comprehensively evaluate the impact of pre-existing health conditions, known as comorbidities, on trauma patient outcomes. A thorough search of pertinent databases was conducted to find studies that satisfy the requirements for inclusion. A thorough search of PubMed, MEDLINE, and Embase was conducted to find pertinent literature. The Rayyan QRCI was used during the whole operation. Seven studies including 1,555 patients total [740 (47.6%) of them were males] were included in the current data. The use of warfarin was linked to a higher 30-day death rate in patients who had normal physiology upon admission, more unfavorable outcomes, and increased morbidity. Hyperglycemia is linked to a poor prognosis and it might serve as a predictor for hospital stay, injury severity score, Glasgow Coma Scale on arrival, intensive care unit (ICU) stay, and death rate. Diabetes and a history of head injury were significantly associated with poor outcomes in head trauma patients. Following trauma, there was a significant correlation between the development of cerebral secondary stress headache and preexisting diabetes, hypertension, history of cerebral infarction, and antiplatelet drugs. This systematic review found that warfarin use, hyperglycemia, diabetes, and a history of head injury were all significantly associated with poorer outcomes among head trauma patients. Future prospective and longitudinal studies are required to investigate the associated comorbidities in head trauma patients.
Key words: Comorbidities, head trauma patients, outcomes, complications, systematic review
|
