Guillain-Barre Syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. Diabetic ketoacidosis (DKA) is a serious, life-threatening complication of Type 1 diabetes mellitus (DM). In the pathogenesis of Guillain-Barre Syndrome and DKA, autoimmunity plays a role. A thirty-five year old male patient, who had been followed up in endocrinology service with a diagnosis of diabetic ketoacidosis (DKA), complained of weakness in the arms and legs on the seventh day of hospitalization. The patient had no diseases except for diabetes mellitus type 1. The patient was diagnosed with Guillain Barre Syndrome (GBS) on the basis of neurological examination, cerebrospinal fluid results and electrophysiological findings. Clinical improvement was observed as a result of intravenous immunoglobulin therapy. Diabetic ketoacidosis induced GBS was considered for the patient. There is no study that points to diabetes mellitus or DKA as risk factors for GBS. Case reports of Guillain Barre Syndrome associated with diabetic ketoacidosis are rare in the literature.
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