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Original Article



Dexmedetomidine versus Labetalol for induced hypotension during functional endoscopic sinus surgery: A randomized, double-blind study

SAVITA GUPTA, ISHA YADAV, ANUPRIYA SAXENA, RAHUL KUMAR BAGLA, NAZIA NAZIR.




Abstract

Background & Objective: Functional endoscopic sinus surgery (FESS) is a surgical procedure for treating sinus diseases. Bleeding is a common concern during FESS, so maintaining hemodynamic stability and ensuring quality surgical field visibility is crucial for achieving the best outcomes. The present study primarily intended to compare the time taken to achieve target MAP between dexmedetomidine and Labetalol during FESS and assess the quality of the surgical field.
Methodology: The present study was conducted as a prospective, randomized, double-blinded clinical study. Sixty patients classified as American Society of Anesthesiologists grade I or II status, undergoing FESS under general anesthesia, were divided into two groups, each with 30 members. The patients receiving dexmedetomidine and labetalol were named groups D and L, respectively. The study aimed to maintain the mean arterial pressure (MAP) between 60-70 mmHg. The operative field visibility was assessed using the Fromme and Boezaart scoring system. Emergence time and postoperative first analgesic request time were also recorded.
Results: The time taken to achieve target MAP (60-70 mmHg) was less in group D (15.1± 0.2 min) than in group L(18.2± 0.5 min), and it was statistically significant (P

Key words: Dexmedetomidine, Labetalol, Controlled Hypotension, Mean Arterial Pressure






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