Comparative Study of the Analgesic Activity of Two Iraqi Medicinal Plants, Ruta graveolens and Matricaria chamomilla Extracts
Saad Abdulrahman Hussain, Intesar Tariq Numan, Maha Noori Hamad.
Abstract
Aims: The study was performed to compare the analgesic activity of different fractions of the extracts of Ruta graveolens and Matricaria chamomilla.
Materials and Methods: The plant materials were extracted with 70% ethanol, petroleum ether, ethyl acetate and n-butanol. The ethyl acetate and n-butanol fractions of each plant were evaporated to dryness and analyzed by HPLC. The analgesic activity of these extracts was evaluated using writhing reflex test and compared with that produced by a standard drug (Diclofenac sodium).
Results: Flavonoids were found in all fractions of both plants (i.e ethyl acetate and n-butanol), while trace of alkaloids in were found in the ethyl acetate fraction of Ruta. The prepared extracts showed better analgesic activity than the standard drug; when compared with each other, Matricaria extracts showed better analgesic activity compared to Ruta extracts.
Conclusion: There is similar efficacy of chamomile and common rue as analgesic agents.
The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
We use cookies and other tracking technologies to work properly, to analyze our website traffic, and to understand where our visitors are coming from. More InfoGot It!
