Background: Colorectal carcinoma (CRC) is the third cause of cancer-related death worldwide.
Methods: This study aimed to assess the clinicopathological parameters and their correlation with prognosis in patients with CRC. Two hundred pathology reports for cases diagnosed with CRC in Doctor Soliman Fakeeh Hospital in the period 2000 to 2023 were retrieved from the archives and the Yasashi database of Fakeeh Hospital for reviewing the clinical and pathological data. Univariate & multivariate analyses were conducted.
Results: A total of 50 reports were included in the study. In regard to the relation between clinicopathological findings and the prognosis of CRC, there was a statistically significant relation between the grade of the tumor and its metastasis (p-value = 0.024). However, there was a statistically insignificant relationship to gender, age, diabetes mellitus status, neoadjuvant chemotherapy, surgical operation, location of the tumor, and invasion of the surrounding tissues.
Conclusion: The study highlighted the significant correlation between clinicopathological findings, particularly the grade of the tumor, and the prognosis of CRC. Factors like tumor size, metastasis, and histological grade played crucial roles in determining the prognosis of CRC patients.
Key words: pathological features, molecular markers, colorectal cancer, prognosis, survival
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