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Evaluation of Bladder Carcinoma Risk of the Workers Exposed to Industrial Chemicals

Serpil,Oğuztüzün,,Murat,Kılıç,,Nisa,Tandoğan,,Latif,Öztürk,,Zuhal,Yazıcı,Gökbulut.




Abstract

AIM: The aim of this study is to evaluate the ratios of bladder carcinoma of workers exposed to industrial chemicals in Kırıkkale, Turkey by urinary cytology method.
METHOD: Urinary cytology preparations for a total of 63 workers in the gun powder production plant was prepared using Papanicolaou staining and evaluated by light microscopy. The relationship between Papanicolaou staining results and workers’ exposure time to chemicals was evaluated statistically by Post Hoc Test method.
RESULTS: For the cytological diagnoses of voided urine in all 63 workers, 16 workers as control group had negative cytologic findings. 47 workers exposed to industrial chemicals more than 20 years had two metaplasic and two dysplasic cells in their urine cytology samples. Moreover, a worker exposed to industrial chemicals more than 30 years had urothelial carcinoma cells.
CONCLUSİON: That the workers’ risk of developing bladder carcinoma increases with their exposure time to chemicals in their work environment has been found statistically significant (p

Key words: Urine Cytology, Bladder Carcinoma, Chemical Carcinogens

Article Language: Turkish English






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