ABSTRACT
Background: With the increasing importance of personalized patient management, effective analysis of various patient data can play an important role in identifying people at risk of high-burden diseases like diabetes mellitus(DM). By studying the correlation between DM and blood groups, potential risk factors can be identified, leading to personalized strategies for screening and prevention.
Objectives: This study aims to investigate the association between type 2 DM (T2DM) and different blood groups.
Materials and Methods: Date was extracted from a population database of Mashhad Health Care Centers, the second metropolitan city in Iran. From 169,536 individuals who were referred for DM management, data of 6801 persons was extracted. The control group consisted of non-diabetic individuals, who were matched in terms of sex and age. Demographic variables, medical history, and blood groups were obtained.
Results: The mean(SD) age of diabetic individuals was 41.3(8.6) years, 80% being overweight or obese. Among T2DM patients, blood type O was the most common, followed by A, and blood type AB had the lowest prevalence (32.7%, 30.6%, and 9.3% respectively). Compared to the control group, Blood type O showed a higher prevalence in DM (P-value=0.001). Diabetic persons with blood type O had a higher occurrence of T2DM in their family history (P-value=0.01).
Conclusion: In patients with T2DM, the most frequent blood type was O, with A coming in second. It seems that those with O+ blood type are more susceptible to developing T2DM. Additionally, differences and inconsistencies have been noted among various countries, hinting at the possible impact of other factors.
Key words: Blood Group, Diabetes Mellitus, T2DM, Personalized Patient Management
|
