Wernickes encephalopathy in a case of
tuberculous meningitis
Dr. Amit Agrawal 1.
Abstract
Wernickes encephalopathy is an acute neuropsychiatric condition due to an initially reversible biochemical
brain lesion caused by overwhelming metabolic demands on brain cells that have depleted intracellular
thiamine (vitamin B1). If untreated thiamine deficiency is associated with high rate of mortality and
morbidity. Wernickes encephalopathy should be high on the differential of any patient at risk for malnutrition
or with ophthalmoplegia. This is particularly important in patients where the syndrome may be masked by
any other associated neurological disorders and can cause delay in the treatment
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