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Research Article

CUJOSTECH. 2024; 1(2): 21-26


Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis

Friday Attah, Moses E Abalaka.




Abstract

Plants have served as a traditional remedy for humans throughout history, due to their availability, perceived safety, and easy access. Mitracarpus scaber, a herb historically appreciated for its usefulness in treating various skin problems, was the focus of this current research aiming to identify the plant's phytocompounds content using Fourier-transform infrared spectroscopy (FTIR) and gas chromatography-mass spectrometry (GC-MS) methods. The presence of phenols, saponins, flavonoids, steroids, alkaloids, tannins, and terpenoids were identified through phytochemical screening. The plant's chemical composition was analysed by FTIR, the results indicate the presence of the following functional groups: C=C, C-Cl, C-N, S=O, C-N, O-H, N-O, C=O, C-H, and N-H. The GC-MS result revealed 18 phytocompounds, with the following being the most abundant: Oleic acid (23.22%), n-Hexadecanoic acid (14.60%), 1, 3-dioxolane (13.50%), 11-Octadecenoic acid, methyl ester (10.12%), Hexadecanoic acid, methyl ester (9.18%), 4-Trifluoroacetoxy hexadecane (5.97%), Octadecanoic acid, methyl ester (4.58%), and Stearic acid methyl ester (3.08%), all of which have medicinal value. The study revealed Mitracarpus scaber's medicinal potential, emphasizing its importance in pharmaceutical research and the development of novel drugs, particularly for skin infections. More pharmacological research is needed to fully explore the therapeutic effects of these bioactive substances on skin disease causative agents.

Key words: GC-MS, FTIR, Phytoconstituent, Phytochemical and Plant






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