Aya Chendooram is a Siddha drug, used for various aliments in India. The present study is to evaluate the anti-ulcerogenic property of Aya Chendooram in aspirin- induced ulcerogenesis in pylorus ligated rat model and analyze for gastric volume, ulcer score, pH, free and total acidity and sodium and potassium ion output. Bio-chemical estimations like total proteins, total hexoses, hexosamine, fucose, sialic acid and pepsin were also carried out. The results investigated that the drug has antiulcer activity through the inhibition of aggressive factors and increasing the defensive factors.
Key words: Anti-ulcerogenic activity, Aya chendooram, Siddha drug.
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