Abstract

The anti-inflammatory activity of petroleum ether ethyl acetate and methanolic
extracts of Ximenia americana L. was investigated in chemical models - using carrageenan induced
paw oedema. Ximenia americana is the most common plant widely grown in tropic and sub tropical
climatic conditions and is used in rheumatism and dropsy.1 The preliminary phytochemical
screening of the plant shows the presence of sterols, terpenoids, alkaloids, tannin, saponin and
phenolic compounds3 which are responsible for various pharmacological activities. The leaf extract
of the Ximinia americana were used to evaluate anti-inflammatory activity. The result proved that
petroleum ether and methanolic extract of the plant has anti-inflammatory activity.

Key words: Ximenia americana, Ximenia spinosa salisb, Anti-inflammatory, Plethysmograph, Carrageenan, Formalin, Paw oedema.