Persistent viral infection with high-risk human papillomavirus (HPV) genotypes causes virtually all cancer of the cervix. The same HPV genotypes (“types”) also cause cases of anal cancer. Cervical cancer is the third most frequent cancer in women worldwide after breast and colorectal cancers. It ranks fourth of women’s cancers according to the mortality ratio. Two vaccines have been developed against HPV infection; one is a quadrivalent vaccine (Gardasil™) and the other is a bivalent vaccine (Cervarix™). This topic will cover issues related to HPV infections, routine HPV immunization recommendations, vaccination in special patient populations, the cost-effectiveness of HPV vaccination, and vaccine safety.
Key words: HPV,
vaccine,
cervical cancer Article Language: Turkish English
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