INCREASING SERUM LEVEL OF TUMOR NECROSIS FACTOR ALPHA IN SOME GASTROINTESTINAL CANCERS IN IRAQI PATIENTS
Ahmed R. Abdullah
Shaimaa Y. Abdulfattah
Ali H.M. Ali
Bara A. Abdulhameed.
Abstract
Gastrointestinal cancers (GITs) are a worldwide problem particularly in the highly developed countries. In Iraq , gastric cancer(GC) is the 9th most common cancer while colorectal cancers (CRC) is considered as the 7th most common cancer among all cancer patients in both males and females. The Objective of this study was to estimate the serum level of Tumor Necrosis factor alpha (TNF-α) in some Iraqi colorectal and gastric cancer patients. In this study, 54 serum samples were collected starting from the 1st of January till the mid of March 2011 to investigate the TNF-α serum level by using ELISA technique. Thirty eight samples were gastric (H. pylori +ve) and colorectal cancer patients (GC=17, CRC=21) and 16 samples considered as a healthy control group. The results showed that TNF-α serum levels of both GIT tumors were increased significantly (P
Key words: TNFα, Colorectal Cancer, Gastric Cancer
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