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Dyslipidemia in hypothyroid subjects with Hashimoto’s thyroiditis

Somasundaram Hariharan, Somanath Padhi, Jayaprakash Sahoo, Rajlaxmi Sarangi.




Abstract
Cited by 0 Articles

Background: The relationship between hypothyroidism and dyslipidemia is poorly understood.

Objective: We aimed to describe the relationship between serum thyroid-stimulating hormone (TSH) and fasting lipid profile.

Materials and Methods: This prospective study recruited 50 hypothyroid subjects with Hashimoto’s thyroiditis who attended the endocrinology clinic of a teaching hospital from August 2011 to October 2011.

Results: Serum TSH showed positive correlation with serum total cholesterol, triglyceride, and low-density lipoprotein cholesterol, but had negative correlation with high-density lipoprotein cholesterol (P > 0.05).

Conclusion: Hypothyroidism leads to atherogenic lipid profile. However, our observation needs to be further validated by larger prospective studies.

Key words: Dyslipidemia, Hashimoto’s thyroiditis, hypothyroidism






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