Malignant mesothelioma of the tunica vaginalis is rare. The etiology is unclear. Exposure to asbestos is attributed as one of the risk factor. It is commonly seen in the elderly age group with hydrocele as the presenting complaint. Diagnosis is usually confirmed following histopathological examination, marker studies by immunohistochemistry and electron microscopy. We present a case in a 54 year old male who presented with left scrotal swelling. Immunohistochemically the tumor cells were positive for WT1, keratins, EMA, vimentin and negative for calretinin, desmin, CEA and actin. Ours is a rare case of paratesticular mesothelioma with calretinin negative.
Key words: Calretinin marker, Mesothelioma, Paratesticular mesothelioma
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