Comparative evaluation of amisulpride and escitalopram on Hamilton Depression Rating Scale among depression patients in a tertiary care teaching hospital in Nepal
Background: Depression is a considerable global public health problem and is a major cause of disability and premature death. It results in poor quality of life in patients and caregivers.
Objective: The present study was conducted to compare efficacy and safety of amisulpride and escitalopram, using Hamilton Depression Rating Scale (HAM-D) among depression patients in a tertiary care teaching hospital in Nepal.
Material and Methods: This study was conducted in the Department of Neuropsychiatry, Nepalgunj Medical College and a tertiary care teaching hospital in Nepal for a period of 1 year. A total of 117 depression patients were randomly selected and divided into two groups. Group I (58 patients) received amisulpride 50 mg/day orally and Group II (59 patients) were given escitalopram 10 mg/day orally. The patients were followed up at 4, 8, and 15 weeks. The efficacy of the drugs was calculated by HAM-D. Adverse drug reactions were monitored at every follow-up. GraphPad Instat, version 3.0, tool was used for statistical analysis and p-value
Key words: Depression, amisulpride, escitalopram, Hamilton Depression Rating Scale (HAM-D)
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
We use cookies and other tracking technologies to work properly, to analyze our website traffic, and to understand where our visitors are coming from. More InfoGot It!
