A total of 41 actinomycetes were isolated from marine samples collected in Thailand. On the basis of morphology, chemotaxonomy and 16S rRNA gene sequence analysis, they were identified as Salinispora (13 isolates), Micromonospora (11 isolates), Nocardia (1 isolate), Verrucosispora (2 isolates) and Streptomyces (14 isolates). The antimicrobial activity screening revealed that two Micromonospora isolates, twelve Salinispora isolates, and ten Streptomyces isolates showed activity against Staphylococcus aureus ATCC 25923, Kocuria rhizophila ATCC 9341, Bacillus subtilis ATCC 6633, Escherichia coli NIHJ KC213, Candida albicans KF1 and Mucor racemosus IFO 4581. Based on this study, the production media and strains were the main factors that influenced the antimicrobial activity.
Key words: antibacterial activity, marine actinomycetes, sand, sediment, marine sponges
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