Abstract

Background: Coronavirus disease-19 (COVID-19), a novel viral infection has proved to dismantle the lives of people worldwide and has inflicted a major health crisis making it crucial to study its demographic and outcome profile to safeguard the future generations to the best of our capabilities.

Aims and Objectives: The objective of this study was to analyze observational outcomes of the hospitalized COVID-19 patients.

Materials and Methods: Study was conducted at Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun from October 1, 2020, to September 30, 2021, after approval from the Institutional Ethics Committee. It was a cross-sectional, open-label, and retrospective study that included hospitalized COVID-19 patients confirmed by reverse-transcription polymerase chain reaction testing. Records of patients were obtained with permission from concerned authorities. Appropriate statistical tools were used for analysis. P ≤ 0.05 was considered statistically significant.

Results: Records of 606 hospitalized COVID-19 patients were analyzed and indicated that 359 (59.24%) patients were male and 247 (40.76%) were female. The male: female ratio is 1.45:1. The majority of the patients 228 (37.62%) belonged to age group of 46–60 years. Two hundred and seventy-one (44.72%) patients suffered from associated comorbidities of which diabetes mellitus 87 (32.10%) followed by hypertension 70 (25.83%) were most common. 217 (35.81%) patients required oxygen support. Of 86(14.19%) reported deaths, 60 (69.77%) were male with statistically significant P-value belonged to age group of 61–75 years. Median length of stay of the patients was 7 days.

Conclusion: Majority of patients hospitalized were male and belonged to middle-aged group. Majority of mortalities were among males and belonged to elderly age-group. Most patients with comorbidities were from elderly age-group and diabetes being most common. Continued study on infectivity profile of infected individuals may contribute largely in assessment and formulation of various norms to fight the disease in the future.

Key words: COVID-19; Severe Acute Respiratory Syndrome Coronavirus 2; Angiotensin-Converting Enzyme 2; Reverse-Transcription Polymerase Chain Reaction