Background: Vitamin D deficiency has recently been shown to play a role in insulin resistance and derangement of insulin secretion, which in turn may affect type 2 diabetes adversely.
Aims and Objectives: The objective of this study was to investigate the association between vitamin D deficiency and insulin resistance in type 2 diabetic patients.
Materials and Methods: A cross-sectional observational study was conducted on 100 type 2 diabetic patients aged 30–75 years, with both genders (60 male and 40 female). To analyze, the relationship between vitamin D and glycemic parameters, a Pearson correlation was performed.
Results: In this present study, we found a negative significant correlation between vitamin D and fasting insulin r = −0.33 (P < 0.001) it was also true for homeostatic model assessment-insulin resistance and fasting plasma glucose r = −0.42, r = −0.43 (P < 0.001), respectively. Furthermore, vitamin D was positively correlated QUICKI model in type 2 diabetes mellitus (T2DM).
Conclusion: From the findings, we can conclude that vitamin D deficiency has an important role in insulin resistance hence, vitamin D supplementation could improve glycemic control in T2DM.
Key words: Type 2 Diabetes mellitus; Homeostatic Model Assessment-Insulin Resistance; QUICKI; Fasting Insulin; 25(OH)D
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