Abstract

Background: Androgenic alopecia (AGA) is a pattern of hair loss in men and women characterized by progressive miniaturization that does not cause scarring of hair follicles. Prostaglandin analogues have been recognized as being capable of inducing hypertrichosis.

Objective: To determine the effect and safety of bimatoprost on androgenic alopecia

Methods: Eight subject diagnosed with androgenic alopecia based on history, physical examination and dermoscope, were given 1 drop (≈ 50µL) bimatoprost 0.03% in the target area of therapy once a day for 12 weeks. A dermoscope was used to measure the diameter and number of velus hairs (hair with a diameter less than 1mm)

Result: All target areas of therapy showed an increase in the velus hair diameter after therapy

Conclusion: This study shows that 12-week topical application of bimatoprost 0.03% solution results in a significant increase in vellus hair diameter.

Key words: bimatorpost, androgenic alopecia, vellus hair, diameter